For my patients with immune dysfunction , glutathione is an almost automatic recommendation
Free radicals from UV exposure, pollution, and other environmental stressors can damage skin cells and stimulate melanin production
None of the active ingredients are phototoxic, but azelaic acid and metronidazole may increase sensitivity indirectly
The soluble form of GSTs has been investigated to exist as dimers
32 In another trial, two to three months of treatment with a daily oral supplement providing 200 mg vitamin C as well as 10 mg zinc, 100 mcg selenium, and 400 mg rutin (a flavonoid that may reduce capillary fragility 33 and inflammation related to histamine) 34,35 was compared to standard medical therapy in 30 rosacea patients
This protection is crucial for cellular integrity, potentially reducing damage from environmental factors